regeneration

  1. KJ

    A connectivity mapping approach predicted acetylsalicylic acid (aspirin) to induce osteo/odontogenic differentiation of dental pulp cells

    https://pubmed.ncbi.nlm.nih.gov/32053214/ Results: The GEO database search identified a specific gene expression signature for osteo/odontogenic differentiation. Analysis using ssCMap found that acetylsalicylic acid [(ASA)/aspirin] was the drug with the strongest correlation with that gene...
  2. KJ

    Drug Repurposing for Tooth Regeneration: The Promising Premises

    https://pubmed.ncbi.nlm.nih.gov/35017906/ Drug repurposing which identifies new therapeutic use(s) for drugs currently in use is a brand-new avenue of research interest worldwide. It circumvents the high-end monetary and time investment usually associated with contemporary drug discoveries. In...
  3. KJ

    Effects of Aspirin on Odontogenesis of Human Dental Pulp Cells and TGF- β 1 Liberation from Dentin In Vitro

    https://pubmed.ncbi.nlm.nih.gov/36034475/ Results: The results showed that 25-50 μ·g/mL ASA promoted mitochondrial activity of HDPCs at 72 h (P < 0.05) and yielded significantly higher proliferation rates of HDPCs than the control at 14d and 21d (P < 0.001). All concentrations of ASA promoted...
  4. KJ

    VEGF and odontoblast-like cells: stimulation by low frequency ultrasound

    https://pubmed.ncbi.nlm.nih.gov/18980757/ Results: After 24h cell culture, WST-1 analysis of cell viability and number showed a dose-dependent decrease in the number of viable cells with increasing ultrasound power. However, the relative concentration of VEGF as analysed by ELISA and normalised...
  5. KJ

    Therapeutic ultrasound for dental tissue repair

    https://pubmed.ncbi.nlm.nih.gov/19553029/ https://sci-hub.hkvisa.net/10.1016/j.mehy.2009.05.032 Dental disease affects human health and the quality of life of millions worldwide. Tooth decay (caries) and diseases of the dental pulp result in loss of tooth vitality and function requiring...
  6. KJ

    Low-intensity pulsed ultrasound in dentofacial tissue engineering

    https://pubmed.ncbi.nlm.nih.gov/25672801/ https://sci-hub.hkvisa.net/10.1007/s10439-015-1274-y Non-invasive modality such as LIPUS therapy has been given increased attention and raised as promising therapeutic tool for the regeneration of orofacial tissues. LIPUS presents low toxicity, low...
  7. KJ

    Ultrasound May Help Regrow Teeth

    https://www.sciencedaily.com/releases/2006/06/060628234304.htm El-Bialy first discovered new dental tissue was being formed after using ultrasound on rabbits. In one study, published in the American Journal of Orthodontics and Dentofacial Orthopedics, El-Bialy used ultrasound on one rabbit...
  8. KJ

    Alveolus soft and bone tissue regeneration after laser biomodulation - a histological study

    https://pubmed.ncbi.nlm.nih.gov/32239104/ Functional and esthetic recovery of the patient after tooth extraction is a concern in the nowadays-dental medicine. Immediate implant placement in fresh sockets in posterior sides of the jaws is difficult because of the high amount of bone loss and the...
  9. KJ

    Effects of red light-emitting diode irradiation on dental pulp cells

    https://pubmed.ncbi.nlm.nih.gov/22879579/ Light irradiation activates a range of cellular processes in a variety of cell types, including stem cells, and can promote tissue repair. This study investigated the effects of light-emitting diode (LED) exposure on dental pulp cells (DPCs). Dose...
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