Association of oral contraceptive use with suicidal behavior among representative Korean population: Results from Korea National Health and Nutrition Examination Survey (2007-2016) - PubMed
There is an increased association between OC use and suicidality and the pattern of the relationship differs depending on whether there is a history of depression.
pubmed.ncbi.nlm.nih.gov
Results: A total of 4,067 women (14.0%) reported they had suicide ideations or had attempted suicide, respectively. OC use was associated with an increased prevalence of suicidality (OR = 1.13, 95% CI 1.00-1.24) after adjustments for age, demographic factors, age of menarche, and lifestyle behaviors. When stratified by history of depression diagnosis, ORs linearly increased as the total duration of OC use lengthened among women with a history of depression; however, women without a history of depression showed peaked OR at 4- to 12-month use.
Conclusion: There is an increased association between OC use and suicidality and the pattern of the relationship differs depending on whether there is a history of depression.
