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Aspirin Is Bone Protective
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<blockquote data-quote="KJ" data-source="post: 71199" data-attributes="member: 1"><p>[URL unfurl="true"]https://www.hindawi.com/journals/jos/2017/3710959/[/URL]</p><p>Evidence from cellular and animal studies suggests that <strong>aspirin possesses bone protective effects.</strong> Aspirin is able to promote the survival of osteoblast precursor stem cells and differentiation of osteoblast. It also inhibits the NF<em>κ</em>B pathway, reduces the expression of RANKL, and increases OPG, thus suppressing the differentiation of osteoclast. Thus, bone health deterioration is prevented in aspirin-treated animal subjected to bone loss. The skeletal effects of aspirin in human are limited and inconclusive. <strong>Aspirin may increase bone mineral density of the users,</strong> but this does not translate to fracture prevention. Data from more large-scale prospective epidemiological studies are essential in validating the relationship between the use of aspirin and fracture.</p></blockquote><p></p>
[QUOTE="KJ, post: 71199, member: 1"] [URL unfurl="true"]https://www.hindawi.com/journals/jos/2017/3710959/[/URL] Evidence from cellular and animal studies suggests that [B]aspirin possesses bone protective effects.[/B] Aspirin is able to promote the survival of osteoblast precursor stem cells and differentiation of osteoblast. It also inhibits the NF[I]κ[/I]B pathway, reduces the expression of RANKL, and increases OPG, thus suppressing the differentiation of osteoclast. Thus, bone health deterioration is prevented in aspirin-treated animal subjected to bone loss. The skeletal effects of aspirin in human are limited and inconclusive. [B]Aspirin may increase bone mineral density of the users,[/B] but this does not translate to fracture prevention. Data from more large-scale prospective epidemiological studies are essential in validating the relationship between the use of aspirin and fracture. [/QUOTE]
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Aspirin Is Bone Protective
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