aspirin

  1. KJ

    A connectivity mapping approach predicted acetylsalicylic acid (aspirin) to induce osteo/odontogenic differentiation of dental pulp cells

    https://pubmed.ncbi.nlm.nih.gov/32053214/ Results: The GEO database search identified a specific gene expression signature for osteo/odontogenic differentiation. Analysis using ssCMap found that acetylsalicylic acid [(ASA)/aspirin] was the drug with the strongest correlation with that gene...
    • KJ
    • Thread
    • aspirin dental pulp regeneration
    • Replies: 0
    • Forum: Real Corner
  2. KJ

    Drug Repurposing for Tooth Regeneration: The Promising Premises

    https://pubmed.ncbi.nlm.nih.gov/35017906/ Drug repurposing which identifies new therapeutic use(s) for drugs currently in use is a brand-new avenue of research interest worldwide. It circumvents the high-end monetary and time investment usually associated with contemporary drug discoveries. In...
    • KJ
    • Thread
    • aspirin dental pulp regeneration
    • Replies: 0
    • Forum: Real Corner
  3. KJ

    Effects of Aspirin on Odontogenesis of Human Dental Pulp Cells and TGF- β 1 Liberation from Dentin In Vitro

    https://pubmed.ncbi.nlm.nih.gov/36034475/ Results: The results showed that 25-50 μ·g/mL ASA promoted mitochondrial activity of HDPCs at 72 h (P < 0.05) and yielded significantly higher proliferation rates of HDPCs than the control at 14d and 21d (P < 0.001). All concentrations of ASA promoted...
    • KJ
    • Thread
    • aspirin dental pulp regeneration
    • Replies: 0
    • Forum: Real Corner
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