1/2 a grain of Cynoplus = 26mg~
Most reliable subclinical hypothyroid symptoms: A resting heart rate lower than 85 BPM, a waking oral/armpit temperature lower than 97.8 - 98.2F and an average temperature lower than 98.6F.
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Most commonly, in adults, this is two grains [to correct hypothyroid symptoms]; three grains sometimes are needed, rarely four grains may be required.” — Broda Barnes
“...An eighth to a fourth of a [Cynoplus] tablet would be a reasonable amount to start with; thyroxine’s half-life in the body is two weeks, so the effect is cumulative, and if you get the desired effects in less than two weeks the dose should probably be reduced.” — Ray Peat
“I think 85/minute resting is a good average. For the last 35 years I have tried to keep it averaging a little over 90. When people are using thyroid to recover from tumors or cataracts or other chronic problem, they sometimes hold their resting pulse rate at 100 or more for a few months, without any harmful effects. Sometimes I think you'll be able to figure it out by yourself.” — Ray Peat
Starting Thyroid Supplementation
'Sometimes it takes many months to get the metabolic rate stable at a higher level, and it's often necessary to use a thyroid supplement.
Thyroid is the only thing that safely lowers cholesterol, but when your stress hormones are very high, you shouldn't take more than about one microgram of Cytomel at a time, and should accompany it with things like milk and orange juice.
With your TSH so high, you should probably add a thyroid supplement, until you get it down to about 1.0, or less. (The normal range, according to the American Association of Clinical Endocrinologists, is from 0.3 to 3.0.)
A starting dose of about 1 mcg can produce a noticeable effect, and can be repeated at intervals according to the effect. 5 mcg with a meal is another way to start it. Thyroid tends to lower cholesterol by converting it into pregnenolone and other steroids, and yours is high enough to easily improve your steroid hormone balance.
Cynoplus (
www.farmaciadelnino.com has a good price) is cheaper than Armour, and an eighth to a fourth of a tablet would be a reasonable amount to start with; thyroxine's half-life in the body is two weeks, so the effect is cumulative, and if you get the desired effects in less than two weeks the dose should probably be reduced.
At the beginning, once a day, but if your temperature and pulse and symptoms aren't just right after two weeks you could add another dose at a different time of day. Change of seasons affects the amount of thyroid you need, sometimes it isn't needed after using it for a while, but it's always good to watch for signs of change.'